Select Page

Functional Materials include different projects, all focusing on altering the surface properties of different materials.

 

Current Project:

Antibiotic-producing Coatings

Substrate Mediated Enzyme Prodrug Therapy (SMEPT) is a novel approach that allows for localized drug synthesis directly on the surface of the medical implant. Before the implant is inserted into the body, it can be coated with polymer films containing an immobilized enzyme. In SMEPT, an externally administered, non-toxic, non-therapeutic prodrug is converted to its corresponding active drug when encountering the immobilized enzyme in the coating. This makes it possible to control the administration, to alter the treatment dose and to choose between multiple drugs. This project aims to provide proof-of-concept for the ability of SMEPT to combat in vitro grown biofilms of medically relevant microorganisms.

Read more

Photocatalytic Polymerisation:

Light Induced Surface Functionalisation for Adhesion and Antifouling

Adhesion of polymer brushes on various substrates is fundamental for many different applications in wide ranging industries. Atom transfer is one of the techniques used to synthesize covalently attached polymer brushes on various surfaces.

Read more

Synthesis of RAFT Initiator on Glassy Carbon Surfaces

The aim of this project is to synthesise a RAFT initiator on a glassy carbon surface. The purpose of the initiators is to use them in a photocatalytic polymerisation of polymer brushes in water.

Read more
Bone Promoting Coatings

Combined Effect of Topography and Strontium on Mineralization

It has been established that the osteogenic expression and mineralization of bone-forming cells at surfaces of artificial materials depends on a number of cues including elastic modulus, chemistry, pattern shape as well as topography at the nanometer and micrometer scale. At iNANO, we have developed a topographical screening assay, which has already been able to provide further insight into the interaction between surface topographies and osteogenic differentiation.

 

Read more

 

Previous Projects:

Evanescent Wave Photocatalysis and Photopolymerisation for Surface Functionalisation

Anti-fouling materials are essential in industries ranging from the pharmaceutical industry to the energy industry. Making antifouling materials in a better, smarter, and cheaper way as well as understanding the chemistry and specifications of these materials, are thus very interesting areas of research.

 

Read more

Thin Oxygen Permeable Membranes

A good adhesion between polymer coatings and substrate is essential in many applications, enabling the use of polymer film for various purposes – as barriers towards the environment, as active parts of sensors, etc. The current project focusses on coatings of a gas-permeable polymer film of a few micrometre thickness supported by a glass surface.

Read more

Bone Promoting Coatings

Strontium Functionalized Implants for Accelerated Osseointegration

It has been established that the osteogenic expression and mineralization of bone-forming cells at surfaces of artificial materials depends on a number of cues including elastic modulus, chemistry, pattern shape as well as topography at the nanometer and micrometer scale. At iNANO, we have developed a topographical screening assay, which has already been able to provide further insight into the interaction between surface topographies and osteogenic differentiation.

 

Read more

Project Bank:

Evanescent Wave Photocatalysis for Surface Functionalisation

In this research project, materials will be altered by introducing polymers to the surface by evanescent wave photocatalysis. It is unknown whether this process can be controlled sufficiently to create an even distribution of similar polymers on the relevant surfaces. Introducing polymers to the surface will result in a super-hydrophobic surface and thus inhibit attachment of dirt, molecules, or bacteria.

 

Read more

Chemistry Regenerating Surface Properties

Coating a surface with polymer brushes is an efficient way to change the properties of a surface. However, such processes are normally one-time solutions, with no option for renewing or regenerating the surface properties once the surfaces wear or become fouled. A coating technology that allow regeneration of the surface chemistry would be ideal. One application for renewable coatings is in the antifouling area.

Read more