Bone Promoting Coatings – combined effect of topography and strontium on mineralization
Supervisor: Morten Foss
This project is a continuation of a bachelor project conducted fall 2017. The current student on the project is Stefan Pendlmayr.
The project, is based on findings that strontium concentrations and nanostructures affect bone-cell maturation and development. Different nanostructures (size, distance) affect the boneforming cells; especially the height of the nanostructures affect boneformation.
The findings could potentially result in development of “smart petridishes” with specific cell differentiation potential.
Photocatalysis: Surface initiated Atomic Transfer Radical Polymerization (SI-ATRP)
The project is a collaboration between two labs.
Supervisors: Rikke Louise Meyer and Steen Uttrup Pedersen
Students: Jonas Jensen and Cristina Wullf Damlund Nielsen
The project has been running since January 2017. Current students on the project are Jonas Jensen and Christina Nielsen.
The project focus on a photocatalytic method to grow a dense polymer layer on a surface. Usually metal is used as a catalysis, by using light to catalyze the process; the process becomes less expensive and less biohazardous. Even though catalytic metal is captured in the polymer layer in standard production methods, the metal will be released in a marine environment after exposure to stress and end up in the food-chain.
The end group of the polymers are easy to modify or replace in order to introduce desired properties to the coating. In this project, anti-fouling property is the goal. Furthermore, light-induction makes it possible to introduce patterns in the coating by shielding some of the surface.
This project will forward investigate antifouling properties of different polymers through flow cell setups.
Read more about the project: http://spoman-os.org/renewable-surface-chemistry-2/
Updates and data is found here: https://osf.io/f5hyn/ and here: https://osf.io/aqesr/
Mechanics of contacting surfaces
By Ramin Aghababaei
This project is suggested as a new SPOMAN project. The project focus on what happens between contacting surfaces. How does the roughness and legth-scale between surfaces affect “surface-collision” and can we predict how the collision/surface destruction will happen. The simulation could be made for materials of different properties but the initial focus is on metals.
The knowledge will help us design better coatings (thickness, roughness etc. for different materials)
By Marcelo Dias
This project is suggested as a new SPOMAN project. The project focus on how careful choice of geometry inside structure affect mechanical behavior and dynamic of the material. Metamaterials have been used for i.e. shoe soles. If you have input to, in which areas, future products or developments metamaterials could make a difference, please contact us. The project is open to new partners.
Substrate Mediated Enzyme Prodrug Therapy (SMEPT)
This project focus on a new strategy for disrupting biofilm growth using Substrate Mediated Enzyme Prodrug Therapy (SMEPT). Infections after implant surgery is a large problem. Implants coated with polymer films containing an immobilized enzyme allows for drug activation directly at the site of infection. An externally administered, non-toxic, non-therapeutic prodrug is converted to its corresponding active drug when encountering the immobilized enzyme in the coating. This makes it possible to control the administration, to alter the treatment dose and to choose between multiple drugs.
Read more about the project: http://spoman-os.org/antibiotic-producing-coatings/