Bone Promoting Coatings
Student: Carla Martin
Strontium (Sr) is known to promote the formation of bone. This has led to a number of coatings  and surface treatments containing Strontium, aimed at implants in contact with bone. A few studies has also reported an antibacterial effect of released Strontium . A detailed mapping of the Sr-release is the basis for examining a possible combined antibacterial and bone-promoting effect of such coatings.
In this project we will characterize the actual release-rate and the resulting concentrations of Strontium, found at the bone/implant interface, subsequent to implantation. The technology that will be examined during this project will be based on Ti-O-Sr coatings prepared by physical vapour deposition (PVD). The research will be utilizing a setup resembling real in vivo applications.
- PVD for producing the coatings
- XPS for chemical analysis of surface/release volume
- EDX for further chemical characterization of the coating chemistry
- ICP-AES for Sr release studies
- Mammalian and potentially bacterial cell cultures
: O. Z. Andersen et al, Biomaterials, 34 (2013) 5883-5890, : D. S. Brauer et al., J. R. Soc. Interface, 20120647